Kevin, I would highly recommend the 350 gn Barnes. My step Dad just got back from Africa in late September and he used the 350 Barnes on both a lion and a cape! The Barnes at 100 yds shot amazingly accurate for a big bore, we even took pictures I will try to get posted later of the target! Anyhow the PH over there could not get over the combo of the 416 WBY and Barnes bullet, he claimed that he had never in all his yrs of hunting cape, seen one drop so fast and quick with only one shot! My step Dad claimed they didn't stop talking about it at camp the entire rest of his stay, and just kept looking at and holding that perfectly mushroomed X! They said they have seen many of cape run and run after getting several shots into them with 416 rigby's, .458 win's, and 470 nitros, using rounded solids and rounded expanding bullets, but had never in 150 hunts seen one just drop in its tracks like that! They recovered the bullet just under the hide on the far side of the cape and it is mushroomed out beautifully and still weighs 350gns! I will try to post a pic of the recovered bullet too if I get over to his house and take a pic of it! I'm no expert but after seeing how well that bullet shot and performed on two of the most dangerous game in the world I highly recommend it.