If I were going to hunt with a pistol/handgun caliber such as a 44 mag, 45 Colt, 454 Casull and I were huntings anything tougher than a large mule deer such as elk, moose, bear, large hogs within the handguns effective range it would be any of the better very hard cast LBT molds (Lead bullet Technology) styles, SSK molds makes a decent design, Nei makes a good mold, rcbs, lyman , H&G old school, Old ideal molds, any mold with a large cutting band & nose such as the better Keith style swc (semi wad cutter) molds, Magma makes great molds and I'm a little Bias since the founder's kids and I are child hood friends and have at one time owned most of their equipment they can convert / mill a few other 1 or 2 cavity manufacturers iron molds I have a couple I got used for use in their master casters and bullet master automated machines. Anything made out of hardened Linotype alloys with or without gas checks depending on how hard the lead is. Any of these bullets should have a wide Meplat (big flat tip). Since I make my own for some of our guns and have for many years, in the 44 mag I like Heavy per caliber bullets in most cast bullet calibers, such as LBT 300 gr wide flat nose or Long flat nose, (chances of leading barrels is down when using heavy per caliber bullets and of course lead hardness and barrel condition i.e. pitted worn out barrels play a huge part also). Linotype and 2-6 or 2-7 cast bullet alloys are a lot harder than most jacketed/plated hunting bullet cores whether it's a rifle or handgun bullets. Cast bullets alloys that are made specific costs quite a bit more to make and buy vs a standard cup and core bullet which the jacket is the hardest part of their bullet and the lead core is usually swaged in which soft cheaper to buy lead is used to create some expansion in handguns and they don't always expand as advertised, hence the use of very hard & wide Meplat handgun bullets that will drive deep and don't need to expand because they are already wide to begin with. These big companies IMO generally buy lead based on the London metal exchange rates and they buy in tonnage amounts or they have other resources where they can buy materials. If you were going to use some of these extra hard bullets in a semi-auto the big flat Meplat may not cycle correctly and will need to choke down tip diameter something like a Truncated cone design to feed properly that's what I use in the 9 mm 147 grain & 10 mm 200 grain in semi-autos and I don't gas check these they are hard enough with full power loads. The only extra step I've had to do when re-loading these big heavy bullets especially the 320's and some others is they need to be seated in 2 stages to be able to crimp. I had guys tell me the LBT's in 44 mags used in Alaska will blow right thru a Bull Moose broad side at handgun range. In the 44's , 357's , 45's, I strictly use the powder than gives the highest velocities normally H-110 or Win 296. I do like the old HS-7 now discontinued powder in the 10 MM auto. There are a couple other powders that will fill the bill these are just my favorities for this application. For penetration testing I use Oak rounds and measure the depth, Bullet proof glass sometimes at handgun velocities, sand, sometimes wet news papers. Most of the time these very hard bullets don't deform a whole lot they may smear the nose a little just like they are suppose to do. I've even tried them in a 458 win mag full power loads in an oak round, I guess that's why they use solids on Elephants. To be honest I rarely buy 30-30 , 35 rem, 458 dia jacketed rifle bullets because for my purposes I can run full power loads at a substantial cost savings accuracy is on par with factory jacketed bullets, and in these applications they work just fine.
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