I've shot a lot of targets with my 30-378, and one elk. I've not had the greatest of luck with longer projectiles. I use monolithic (copper bullets) in case I have to use it in CA, and actually, I think they're good bullets. anyway, and I don't like thinking of injesting the lead from a shot animal. The twist rate is really a length issue. The longest bullets I've tried are the 200 gr. Barnes LRX bullets. Accuracy is OK as long as I use a very slow powder. Best accuracy has been with H50BMG, believe it or not. Yet I can't get decent accuracy out of US869, Retumbo, or Norma 217, for example. Reloader 33 has shown some promise, as has IMR 8133. Now it's tough to get powder, so it's been a few months. I'm thinking the bullet is a bit long for 1/10" twist, so I bought a bunch of 180 gr Nosler E-Tips for experiment. By the time I get a really good load, the barrel will be shot out LOL!!