I strongly suggest that you do a serious cleaning of the bore and action before you shoot it, but it has almost certainly been broken in.
I have only a few suggestions. First, never shoot so quickly that your barrel gets too hot. Second, a dirty barrel will screw up your accuracy. Keep your barrel VERY clean. And last, take your time and savor every moment. Make the release of tons of energy from your barrel become one of those "Zen moments" of perfection. That's what makes Weatherby what it is!